Drug intelligence / Profile preview

n-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine

Development stage
Unknown
Modality
Small Molecules
01

Overview

n‑cyclopropyl‑4‑(pyrazolo[1,5‑b]pyrindizin‑3‑yl) pyrimidine amine is a small molecule organic compound belonging to the class of aminopyrimidines and derivatives. It has been identified as an inhibitor of cyclin-dependent kinase 2 (CDK2), with reported IC50 values around 120 nM. The compound is primarily investigated for its potential as a kinase inhibitor in drug discovery research. There is no publicly available information on specific clinical indications or advanced development status for this compound at present.[1][6]

Other names
N-Cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)-2-pyrimidinamineN-Cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)-2-pyrimidinaminN-Cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidinamineN-Cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrinmidinaminen-[cyclopropyl]-4-[{1H-pyrazolo}[1,5-b]pyrindizin]-3-yl} pyrimidine amine (various spellings and formats may exist in literature)551919–54–1 (CAS-like number from ChemSpider)[6]
02

Targets

CDK2 (Cyclin-dependent kinase 2)

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